Making game plugins/agents for games that have launchers


I want to look into making a 1v1 bot or aram bot for league of legends. Thought following the tutorials a few months back all of the games were self contained. League of legends has a launcher (with champ select and login).

There are two different .exe programs (the launcher and the client)

Would the set up for a game like this be the same as a regular set up?